Jim Rugg pointed out this interesting piece on the Next Issue blog, in which R. Sikoryak's Masterpiece Comics, Matt Madden's Exercises in Style, and Jim Rugg and Brian Maruca's Afrodisiac.
It struck me that there is significant overlap between what I enjoy about all three listed works, and what I enjoy about mashups and crossbred fiction. A kind of friction between disparate elements, and interesting sparks sent flying by unlikely elements sent colliding into one another.
Some interesting thoughts in Mutch's piece, worth checking out. (And if you haven't read any of referenced works, what the heck are you waiting for?!)